Involvement of the PTEN–AKT–FOXO3a pathway in neuronal apoptosis in developing rat brain after hypoxia–ischemia

The proapoptotic function of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) phosphatase has been linked to its capacity to antagonize the phosphatidylinositol-3-kinase–Akt signaling pathway. Previous studies have shown that the Forkhead transcriptional factor (FOXO3a) is a critical e...

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Hlavní autoři: Li, Deyuan, Qu, Yi, Mao, Meng, Zhang, Xiaolan, Li, Jinhui, Ferriero, Donna, Mu, Dezhi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846558/
https://ncbi.nlm.nih.gov/pubmed/19623194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.102
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