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Signaling pathway involved in hypoxia-inducible factor-1α regulation in hypoxic-ischemic cortical neurons in vitro

Hypoxia-inducible factor-1α (HIF-1α) is a key transciptional regulator of cellular and systemic oxygen homeostasis. Previous studies have shown that the regulation of HIF-1α is involved in the activation of PI3K/Akt pathway in some cells. However, whether this pathway plays a role in modulating HIF-...

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Detalhes bibliográficos
Main Authors: Zhang, Li, Qu, Yi, Yang, Chunlei, Tang, Jun, Zhang, Xiaolan, Mao, Meng, Mu, Dezhi, Ferriero, Donna
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881660/
https://ncbi.nlm.nih.gov/pubmed/19553016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2009.03.091
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