Involvement of the PTEN–AKT–FOXO3a pathway in neuronal apoptosis in developing rat brain after hypoxia–ischemia

The proapoptotic function of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) phosphatase has been linked to its capacity to antagonize the phosphatidylinositol-3-kinase–Akt signaling pathway. Previous studies have shown that the Forkhead transcriptional factor (FOXO3a) is a critical e...

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Detalhes bibliográficos
Main Authors: Li, Deyuan, Qu, Yi, Mao, Meng, Zhang, Xiaolan, Li, Jinhui, Ferriero, Donna, Mu, Dezhi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846558/
https://ncbi.nlm.nih.gov/pubmed/19623194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.102
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