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Development of an Activity Assay for Discovery of Inhibitors of Lipopolysaccharide Transport

The outer membrane of Gram-negative bacteria contains an outer leaflet composed of lipopolysaccharide (LPS) that is transported to this location by a pathway that is essential for viability. It has been suggested that inhibitors of this pathway could be useful antibiotics. Herein we reconstitute the...

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Detalhes bibliográficos
Main Authors: Gronenberg, Luisa S., Kahne, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846522/
https://ncbi.nlm.nih.gov/pubmed/20136079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910361r
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