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Validation of inhibitors of an ABC transporter required to transport lipopolysaccharide to the cell surface in Escherichia coli

The presence of lipopolysaccharide (LPS) in the outer leaflet of the outer membrane (OM) of Gram-negative bacteria creates a permeability barrier that prevents the entry of most currently available antibiotics. The seven lipopolysaccharide transport (Lpt) proteins involved in transporting and assemb...

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Detalhes bibliográficos
Main Authors: Sherman, David J., Okuda, Suguru, Denny, William A., Kahne, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821166/
https://ncbi.nlm.nih.gov/pubmed/23665139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.04.020
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