Activity of epiroprim (Ro 11-8958), a dihydrofolate reductase inhibitor, alone and in combination with dapsone against Toxoplasma gondii.

We examined the effect of epiroprim (Ro 11-8958), a dihydrofolate reductase inhibitor, alone and in combination with dapsone, against Toxoplasma gondii. In vitro, the anti-T. gondii effects of epiroprim and dapsone were observed at nanogram-per-milliliter levels when a 72-h uracil assay and an infec...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Chang, H R, Arsenijevic, D, Comte, R, Polak, A, Then, R L, Pechère, J C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284639/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7986011/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.8.1803
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