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Effect of Recql5 deficiency on the intestinal tumor susceptibility of Apc(min) mice

AIM: To investigate whether Recql5, a DNA helicase that plays an important role in the maintenance of genome integrity, is a tumor suppressor in the gastrointestinal tract in mice. METHODS: We generated cohorts of both Recql5-proficient and Recql5-deficient Apc(min/+) mice and compared the tumor sus...

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Main Authors: Hu, Yiduo, Lu, Xincheng, Luo, Guangbin
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846253/
https://ncbi.nlm.nih.gov/pubmed/20333788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i12.1482
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