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Structural insights into interferon regulatory factor activation
The Interferon Regulatory Factors (IRFs) play important roles in development of the immune system and host defense. Recent crystallographic and biochemical studies have provided insights into the mechanism of activation of IRFs by phosphorylation. The activation of a latent closed conformation of IR...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846214/ https://ncbi.nlm.nih.gov/pubmed/20043992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.12.005 |
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