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Structural insights into interferon regulatory factor activation

The Interferon Regulatory Factors (IRFs) play important roles in development of the immune system and host defense. Recent crystallographic and biochemical studies have provided insights into the mechanism of activation of IRFs by phosphorylation. The activation of a latent closed conformation of IR...

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Detalhes bibliográficos
Main Authors: Chen, Weijun, Royer, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846214/
https://ncbi.nlm.nih.gov/pubmed/20043992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.12.005
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