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Role of Hydroquinone-Thiol Conjugates in Benzene-Mediated Toxicity
Hydroquinone (HQ) is a metabolite of benzene, and in combination with phenol (PHE), reproduces benzene myelotoxicity. HQ readily oxidizes to 1,4-benzoquinone (1,4-BQ) followed by the reductive addition of glutathione (GSH). Subsequent cycles of oxidation and GSH addition give rise to a variety of mo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846198/ https://ncbi.nlm.nih.gov/pubmed/20034486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2009.12.016 |
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