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MicroRNAs and copy number changes: New levels of gene regulation in acute myeloid leukemia

Alkylating agents, topoisomerase II inhibitors, ionizing radiation, and other hematotoxins induce DNA damage in hematopoietic stem cells that results in lesions such as balanced and unbalanced chromosome rearrangements, −5/del(5q) and/or −7/del(7q), as well as other submicroscopic genetic lesions. T...

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Bibliografische gegevens
Hoofdauteur: Larson, Richard A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846194/
https://ncbi.nlm.nih.gov/pubmed/19822134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2009.10.002
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