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MicroRNAs and copy number changes: New levels of gene regulation in acute myeloid leukemia
Alkylating agents, topoisomerase II inhibitors, ionizing radiation, and other hematotoxins induce DNA damage in hematopoietic stem cells that results in lesions such as balanced and unbalanced chromosome rearrangements, −5/del(5q) and/or −7/del(7q), as well as other submicroscopic genetic lesions. T...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846194/ https://ncbi.nlm.nih.gov/pubmed/19822134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2009.10.002 |
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