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MicroRNAs and copy number changes: New levels of gene regulation in acute myeloid leukemia

Alkylating agents, topoisomerase II inhibitors, ionizing radiation, and other hematotoxins induce DNA damage in hematopoietic stem cells that results in lesions such as balanced and unbalanced chromosome rearrangements, −5/del(5q) and/or −7/del(7q), as well as other submicroscopic genetic lesions. T...

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Enregistré dans:
Détails bibliographiques
Auteur principal: Larson, Richard A.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846194/
https://ncbi.nlm.nih.gov/pubmed/19822134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2009.10.002
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