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Chemotherapy enhances tumor cell susceptibility to CTL-mediated killing during cancer immunotherapy in mice

Cancer immunotherapy faces a serious challenge because of low clinical efficacy. Recently, a number of clinical studies have reported the serendipitous finding of high rates of objective clinical response when cancer vaccines are combined with chemotherapy in patients with different types of cancers...

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Autors principals: Ramakrishnan, Rupal, Assudani, Deepak, Nagaraj, Srinivas, Hunter, Terri, Cho, Hyun-Il, Antonia, Scott, Altiok, Soner, Celis, Esteban, Gabrilovich, Dmitry I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846048/
https://ncbi.nlm.nih.gov/pubmed/20234093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40269
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