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Autophagy Induced by Conventional Chemotherapy Mediates Tumor Cell Sensitivity to Immunotherapy

Autophagy attenuates the efficacy of conventional chemotherapy but its effects on immunotherapy have been little studied. Here, we report that chemotherapy renders tumor cells more susceptible to lysis by CTL in vivo. Moreover, bystander tumor cells that did not express antigen were killed by CTL. T...

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Publicat a:Cancer Res
Autors principals: Ramakrishnan, Rupal, Huang, Chun, Cho, Hyun-Il, Lloyd, Mark, Johnson, Joseph, Ren, Xiubao, Altiok, Soner, Sullivan, Daniel, Weber, Jeffrey, Celis, Esteban, Gabrilovich, Dmitry I.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577568/
https://ncbi.nlm.nih.gov/pubmed/22942258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2236
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