Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

Injury and loss of podocytes are leading factors of glomerular disease and renal failure. The postmitotic podocyte is the primary glomerular target for toxic, immune, metabolic, and oxidant stress, but little is known about how this cell type copes with stress. Recently, autophagy has been identifie...

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Main Authors: Hartleben, Björn, Gödel, Markus, Meyer-Schwesinger, Catherine, Liu, Shuya, Ulrich, Theresa, Köbler, Sven, Wiech, Thorsten, Grahammer, Florian, Arnold, Sebastian J., Lindenmeyer, Maja T., Cohen, Clemens D., Pavenstädt, Hermann, Kerjaschki, Dontscho, Mizushima, Noboru, Shaw, Andrey S., Walz, Gerd, Huber, Tobias B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846040/
https://ncbi.nlm.nih.gov/pubmed/20200449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39492
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