Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

Injury and loss of podocytes are leading factors of glomerular disease and renal failure. The postmitotic podocyte is the primary glomerular target for toxic, immune, metabolic, and oxidant stress, but little is known about how this cell type copes with stress. Recently, autophagy has been identifie...

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Bibliografische gegevens
Hoofdauteurs: Hartleben, Björn, Gödel, Markus, Meyer-Schwesinger, Catherine, Liu, Shuya, Ulrich, Theresa, Köbler, Sven, Wiech, Thorsten, Grahammer, Florian, Arnold, Sebastian J., Lindenmeyer, Maja T., Cohen, Clemens D., Pavenstädt, Hermann, Kerjaschki, Dontscho, Mizushima, Noboru, Shaw, Andrey S., Walz, Gerd, Huber, Tobias B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2010
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846040/
https://ncbi.nlm.nih.gov/pubmed/20200449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39492
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