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Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors

The Hedgehog (Hh) pathway is essential for normal embryonic development and tissue repair. The role of Hh signaling in hematopoiesis has been studied primarily by modulating the activity of Patched and Smoothened, but results have been conflicting. Some studies demonstrate a requirement for pathway...

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Библиографические подробности
Главные авторы: Merchant, Akil, Joseph, Giselle, Wang, Qiuju, Brennan, Sarah, Matsui, William
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845897/
https://ncbi.nlm.nih.gov/pubmed/20107231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-241703
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