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Investigating Homology between Proteins using Energetic Profiles
Accumulated experimental observations demonstrate that protein stability is often preserved upon conservative point mutation. In contrast, less is known about the effects of large sequence or structure changes on the stability of a particular fold. Almost completely unknown is the degree to which st...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845653/ https://ncbi.nlm.nih.gov/pubmed/20361049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000722 |
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