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Investigating Homology between Proteins using Energetic Profiles

Accumulated experimental observations demonstrate that protein stability is often preserved upon conservative point mutation. In contrast, less is known about the effects of large sequence or structure changes on the stability of a particular fold. Almost completely unknown is the degree to which st...

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Detalhes bibliográficos
Main Authors: Wrabl, James O., Hilser, Vincent J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845653/
https://ncbi.nlm.nih.gov/pubmed/20361049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000722
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