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Structural insights into RNA Processing by the Human RISC-Loading Complex
Targeted gene silencing by RNA interference (RNAi) requires loading of a short guide RNA (siRNA or miRNA) into an Argonaute protein to form the functional center of an RNA-induced silencing complex (RISC). In humans, Argonaute2 (Ago2) assembles with the guide RNA-generating enzyme Dicer and the RNA-...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845538/ https://ncbi.nlm.nih.gov/pubmed/19820710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1673 |
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