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Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival
We have used mouse embryonic fibroblasts (MEFs) devoid of Ras proteins to illustrate that they are essential for proliferation and migration, but not for survival, at least in these cells. These properties are unique to the Ras subfamily of proteins because ectopic expression of other Ras-like small...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845279/ https://ncbi.nlm.nih.gov/pubmed/20150892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.7 |
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