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Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100.

Bicyclams, in which the cyclam (1,4,8,11-tetraazacyclotetradecane) moieties are tethered via an aliphatic bridge (i.e., propylene, as in JM2763) are potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) (E. De Clercq, N. Yamamoto, R. Pauwels, M. Baba, D. S...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: De Clercq, E, Yamamoto, N, Pauwels, R, Balzarini, J, Witvrouw, M, De Vreese, K, Debyser, Z, Rosenwirth, B, Peichl, P, Datema, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1994
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284523/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7913308/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.4.668
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