Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100.

Bicyclams, in which the cyclam (1,4,8,11-tetraazacyclotetradecane) moieties are tethered via an aliphatic bridge (i.e., propylene, as in JM2763) are potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) (E. De Clercq, N. Yamamoto, R. Pauwels, M. Baba, D. S...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	De Clercq, E, Yamamoto, N, Pauwels, R, Balzarini, J, Witvrouw, M, De Vreese, K, Debyser, Z, Rosenwirth, B, Peichl, P, Datema, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284523/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7913308/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.4.668
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