Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans

The small ciliary G protein Arl13b is required for cilium biogenesis and sonic hedgehog signaling and is mutated in patients with Joubert syndrome (JS). In this study, using Caenorhabditis elegans and mammalian cell culture systems, we investigated the poorly understood ciliary and molecular basis o...

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Autores principales: Cevik, Sebiha, Hori, Yuji, Kaplan, Oktay I., Kida, Katarzyna, Toivenon, Tiina, Foley-Fisher, Christian, Cottell, David, Katada, Toshiaki, Kontani, Kenji, Blacque, Oliver E.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2010
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845074/
https://ncbi.nlm.nih.gov/pubmed/20231383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200908133
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