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X-inactivation analysis of embryonic lethality in Ocrl(wt/−);Inpp5b(−/−) mice
Mutations in the human OCRL gene, which encodes a phosphatidylinositol(4,5)bisphosphate 5-phosphatase, result in the X-linked oculocerebrorenal syndrome of Lowe. Mice with a targeted disruption of Ocrl have no phenotypic abnormalities. Targeted disruption of its closest paralog, Inpp5b, causes male...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer-Verlag
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844970/ https://ncbi.nlm.nih.gov/pubmed/20195868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-010-9255-9 |
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