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Conserved regulatory motifs at phenylethanolamine N-methyltransferase (PNMT) are disrupted by common functional genetic variation: an integrated computational/experimental approach

The adrenomedullary hormone epinephrine transduces environmental stressors into cardiovascular events (tachycardia and hypertension). Although the epinephrine biosynthetic enzyme PNMT genetic locus displays both linkage and association to such traits, genetic variation underlying these quantitative...

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מידע ביבליוגרפי
Main Authors: Rodríguez-Flores, Juan L., Zhang, Kuixing, Kang, Sun Woo, Wen, Gen, Ghosh, Sajalendu, Friese, Ryan S., Mahata, Sushil K., Subramaniam, Shankar, Hamilton, Bruce A., O’Connor, Daniel T.
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer-Verlag 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844968/
https://ncbi.nlm.nih.gov/pubmed/20204374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-010-9253-y
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