Dose-dependent antifungal activity and nephrotoxicity of amphotericin B colloidal dispersion in experimental pulmonary aspergillosis.

We investigated the safety and efficacy of amphotericin B colloidal dispersion (ABCD) for the treatment of invasive pulmonary aspergillosis in persistently granulocytopenic rabbits. Treatment groups included ABCD in dosages of 1, 5, and 10 mg/kg/day intravenously or conventional desoxycholate amphot...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Allende, M C, Lee, J W, Francis, P, Garrett, K, Dollenberg, H, Berenguer, J, Lyman, C A, Pizzo, P A, Walsh, T J
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1994
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284491/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8203848/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.3.518
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