Itraconazole for experimental pulmonary aspergillosis: comparison with amphotericin B, interaction with cyclosporin A, and correlation between therapeutic response and itraconazole concentrations in plasma.

Itraconazole and amphotericin B were compared by using a newly developed model of invasive pulmonary aspergillosis in rabbits immunosuppressed with methylprednisolone and cyclosporin A (CsA). Both itraconazole at 40 mg/kg (given orally) and amphotericin B at 1 mg/kg (given intravenously) had in vivo...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Berenguer, J, Ali, N M, Allende, M C, Lee, J, Garrett, K, Battaglia, S, Piscitelli, S C, Rinaldi, M G, Pizzo, P A, Walsh, T J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188202/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8092829/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.6.1303
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