Itraconazole for experimental pulmonary aspergillosis: comparison with amphotericin B, interaction with cyclosporin A, and correlation between therapeutic response and itraconazole concentrations in plasma.

Itraconazole and amphotericin B were compared by using a newly developed model of invasive pulmonary aspergillosis in rabbits immunosuppressed with methylprednisolone and cyclosporin A (CsA). Both itraconazole at 40 mg/kg (given orally) and amphotericin B at 1 mg/kg (given intravenously) had in vivo...

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Main Authors: Berenguer, J, Ali, N M, Allende, M C, Lee, J, Garrett, K, Battaglia, S, Piscitelli, S C, Rinaldi, M G, Pizzo, P A, Walsh, T J
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC188202/
https://ncbi.nlm.nih.gov/pubmed/8092829
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