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Biochemical Analysis of MST1 Kinase: Elucidation of a C-Terminal Regulatory Region

The MST1 kinase phosphorylates FoxO transcription factors in the cytosol and histone H2B in the nucleus to promote cellular apoptosis. In addition to a N-terminal kinase domain, MST1 contains C-terminal regulatory and dimerization regions that are cleaved upon nuclear transport. In this report, we i...

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Hlavní autoři: Anand, Ruchi, Kim, Ah-Young, Brent, Michael, Marmorstein, Ronen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844906/
https://ncbi.nlm.nih.gov/pubmed/18510339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800309m
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