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Biochemical Analysis of MST1 Kinase: Elucidation of a C-Terminal Regulatory Region
The MST1 kinase phosphorylates FoxO transcription factors in the cytosol and histone H2B in the nucleus to promote cellular apoptosis. In addition to a N-terminal kinase domain, MST1 contains C-terminal regulatory and dimerization regions that are cleaved upon nuclear transport. In this report, we i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844906/ https://ncbi.nlm.nih.gov/pubmed/18510339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800309m |
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