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SIRT1 Contains N- and C-terminal Regions That Potentiate Deacetylase Activity
SIRT1 is one of seven mammalian sirtuin (silent information regulator 2-related) proteins that harbor NAD(+)-dependent protein deacetylase activity and is implicated in multiple metabolic and age-associated pathways and disorders. The sirtuin proteins contain a central region of high sequence conser...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2012
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268407/ https://ncbi.nlm.nih.gov/pubmed/22157016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.285031 |
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