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Cross-linking of CD80 on CD4(+) T Cells Activates a Calcium-Dependent Signaling Pathway

CD80 expressed on the surface of antigen presenting cells provides a positive costimulatory signal to naïve CD4(+) T cells via CD28 during activation. However, CD80 is also expressed on the surface of activated CD4(+) T cells, and cross-linking CD80 on the surface of CD4(+) T cells activated in the...

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Detalhes bibliográficos
Main Authors: Podojil, Joseph R., Miller, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844901/
https://ncbi.nlm.nih.gov/pubmed/19124719
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