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MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks
PALB2 physically and functionally connects the proteins encoded by the BRCA1 and BRCA2 breast and ovarian cancer genes into a DNA-damage-response network. However, it remains unclear how these proteins associate with chromatin that contains damaged DNA. We show here that PALB2 binds directly to a co...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Company of Biologists
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844321/ https://ncbi.nlm.nih.gov/pubmed/20332121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.060178 |
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