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Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain

Recognition of acetylated chromatin by the bromodomains and extra-terminal domain (BET) family proteins is a hallmark for transcriptional activation and anchoring viral genomes to mitotic chromosomes of the host. One of the BET family proteins BRD2 interacts with acetylated chromatin during mitosis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Umehara, Takashi, Nakamura, Yoshihiro, Jang, Moon Kyoo, Nakano, Kazumi, Tanaka, Akiko, Ozato, Keiko, Padmanabhan, Balasundaram, Yokoyama, Shigeyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844208/
https://ncbi.nlm.nih.gov/pubmed/20048151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.062422
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