Growth Retardation, Impaired Triacylglycerol Catabolism, Hepatic Steatosis, and Lethal Skin Barrier Defect in Mice Lacking Comparative Gene Identification-58 (CGI-58)

Comparative gene identification-58 (CGI-58), also designated as α/β-hydrolase domain containing-5 (ABHD-5), is a lipid droplet-associated protein that activates adipose triglyceride lipase (ATGL) and acylates lysophosphatidic acid. Activation of ATGL initiates the hydrolytic catabolism of cellular t...

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Main Authors: Radner, Franz P. W., Streith, Ingo E., Schoiswohl, Gabriele, Schweiger, Martina, Kumari, Manju, Eichmann, Thomas O., Rechberger, Gerald, Koefeler, Harald C., Eder, Sandra, Schauer, Silvia, Theussl, H. Christian, Preiss-Landl, Karina, Lass, Achim, Zimmermann, Robert, Hoefler, Gerald, Zechner, Rudolf, Haemmerle, Guenter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Metabolism
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844178/
https://ncbi.nlm.nih.gov/pubmed/20023287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.081877
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