Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation

Adipose triglyceride lipase (ATGL) and its coactivator comparative gene identification-58 (CGI-58) are limiting in cellular triglyceride catabolism. Although ATGL deficiency is compatible with normal skin development, mice globally lacking CGI-58 die postnatally and exhibit a severe epidermal permea...

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Publicado no:J Invest Dermatol
Main Authors: Grond, Susanne, Radner, Franz P.W., Eichmann, Thomas O., Kolb, Dagmar, Grabner, Gernot F., Wolinski, Heimo, Gruber, Robert, Hofer, Peter, Heier, Christoph, Schauer, Silvia, Rülicke, Thomas, Hoefler, Gerald, Schmuth, Matthias, Elias, Peter M., Lass, Achim, Zechner, Rudolf, Haemmerle, Guenter
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551682/
https://ncbi.nlm.nih.gov/pubmed/27725204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.09.025
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