In vitro antiplasmodial, antiamoebic, and cytotoxic activities of a series of bisbenzylisoquinoline alkaloids.

Twenty-four bisbenzylisoquinoline alkaloids were screened for antiplasmoidal, antiamoebic, and cytotoxic activities by use of in vitro microtests. Eight of the alkaloids had antiplasmodial activity, with a 50% inhibitory concentration (IC50) of less than 1 microM against a multidrug-resistant strain...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Marshall, S J, Russell, P F, Wright, C W, Anderson, M M, Phillipson, J D, Kirby, G C, Warhurst, D C, Schiff, P L
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284403/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8141587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.1.96
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