Plants as sources of antimalarial drugs: in vitro antimalarial activities of some quassinoids.

Fourteen quassinoids, obtained from simaroubaceous plants, were tested for in vitro antimalarial activity. All of these inhibited the incorporation of [3H]hypoxanthine into Plasmodium falciparum in vitro at concentrations below 0.41 microgram ml-1. The two most potent quassinoids, bruceantin and sim...

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Autori principali: O'Neill, M J, Bray, D H, Boardman, P, Phillipson, J D, Warhurst, D C, Peters, W, Suffness, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1986
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC176444/
https://ncbi.nlm.nih.gov/pubmed/3530122
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