Plants as sources of antimalarial drugs: in vitro antimalarial activities of some quassinoids.

Fourteen quassinoids, obtained from simaroubaceous plants, were tested for in vitro antimalarial activity. All of these inhibited the incorporation of [3H]hypoxanthine into Plasmodium falciparum in vitro at concentrations below 0.41 microgram ml-1. The two most potent quassinoids, bruceantin and sim...

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Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	O'Neill, M J, Bray, D H, Boardman, P, Phillipson, J D, Warhurst, D C, Peters, W, Suffness, M
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1986
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176444/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3530122/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.1.101
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