Comparative Efficacy of Hemagglutinin, Nucleoprotein, and Matrix 2 Protein Gene-Based Vaccination against H5N1 Influenza in Mouse and Ferret

Efforts to develop a broadly protective vaccine against the highly pathogenic avian influenza A (HPAI) H5N1 virus have focused on highly conserved influenza gene products. The viral nucleoprotein (NP) and ion channel matrix protein (M2) are highly conserved among different strains and various influe...

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Main Authors: Rao, Srinivas S., Kong, Wing-Pui, Wei, Chih-Jen, Van Hoeven, Neal, Gorres, J. Patrick, Nason, Martha, Andersen, Hanne, Tumpey, Terrence M., Nabel, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843722/
https://ncbi.nlm.nih.gov/pubmed/20352112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009812
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