Multivalent HA DNA Vaccination Protects against Highly Pathogenic H5N1 Avian Influenza Infection in Chickens and Mice

BACKGROUND: Sustained outbreaks of highly pathogenic avian influenza (HPAI) H5N1 in avian species increase the risk of reassortment and adaptation to humans. The ability to contain its spread in chickens would reduce this threat and help maintain the capacity for egg-based vaccine production. While...

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Hlavní autoři: Rao, Srinivas, Kong, Wing-Pui, Wei, Chih-Jen, Yang, Zhi-Yong, Nason, Martha, Styles, Darrel, DeTolla, Louis J., Sorrell, Erin M., Song, Haichen, Wan, Hongquan, Ramirez-Nieto, Gloria C., Perez, Daniel, Nabel, Gary J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657001/
https://ncbi.nlm.nih.gov/pubmed/19293944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002432
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