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Hepatitis B Virus X Protein Impairs Hepatic Insulin Signaling Through Degradation of IRS1 and Induction of SOCS3

BACKGROUND: Hepatitis B virus (HBV) is a major cause of chronic liver diseases, and frequently results in hepatitis, cirrhosis, and ultimately hepatocellular carcinoma. The role of HCV in associations with insulin signaling has been elucidated. However, the pathogenesis of HBV-associated insulin sig...

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書目詳細資料
Main Authors: Kim, KyeongJin, Kim, Kook Hwan, Cheong, JaeHun
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843628/
https://ncbi.nlm.nih.gov/pubmed/20351777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008649
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