Cargando...

Impaired Insulin Signaling is Associated with Hepatic Mitochondrial Dysfunction in IR(+/−)-IRS-1(+/−) Double Heterozygous (IR-IRS1dh) Mice

Mitochondria play a pivotal role in energy metabolism, but whether insulin signaling per se could regulate mitochondrial function has not been identified yet. To investigate whether mitochondrial function is regulated by insulin signaling, we analyzed muscle and liver of insulin receptor (IR)(+/−)-i...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Franko, Andras, Kunze, Alexander, Böse, Marlen, von Kleist-Retzow, Jürgen-Christoph, Paulsson, Mats, Hartmann, Ursula, Wiesner, Rudolf J.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485980/
https://ncbi.nlm.nih.gov/pubmed/28556799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061156
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!