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Impaired Insulin Signaling is Associated with Hepatic Mitochondrial Dysfunction in IR(+/−)-IRS-1(+/−) Double Heterozygous (IR-IRS1dh) Mice
Mitochondria play a pivotal role in energy metabolism, but whether insulin signaling per se could regulate mitochondrial function has not been identified yet. To investigate whether mitochondrial function is regulated by insulin signaling, we analyzed muscle and liver of insulin receptor (IR)(+/−)-i...
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| Publicado en: | Int J Mol Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5485980/ https://ncbi.nlm.nih.gov/pubmed/28556799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061156 |
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