Endothelial Fli1 Deficiency Impairs Vascular Homeostasis : A Role in Scleroderma Vasculopathy

Systemic sclerosis or scleroderma (SSc) is a complex autoimmune connective tissue disease characterized by obliterative vasculopathy and tissue fibrosis. The molecular mechanisms underlying SSc vasculopathy are largely unknown. Friend leukemia integration factor 1 (Fli1), an important regulator of i...

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Detalhes bibliográficos
Main Authors: Asano, Yoshihide, Stawski, Lukasz, Hant, Faye, Highland, Kristin, Silver, Richard, Szalai, Gabor, Watson, Dennis K., Trojanowska, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843486/
https://ncbi.nlm.nih.gov/pubmed/20228226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090593
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