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Persistent Down-Regulation of Fli1, a Suppressor of Collagen Transcription, in Fibrotic Scleroderma Skin

The molecular and cellular mechanisms that maintain proper collagen homeostasis in healthy human skin and are responsible for the dysregulated collagen synthesis in scleroderma remain primarily unknown. This study demonstrates that Fli1 is a physiological negative regulator of collagen gene expressi...

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Detalhes bibliográficos
Main Authors: Kubo, Masahide, Czuwara-Ladykowska, Joanna, Moussa, Omar, Markiewicz, Margaret, Smith, Edwin, Silver, Richard M., Jablonska, Stefania, Blaszczyk, Maria, Watson, Dennis K., Trojanowska, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868228/
https://ncbi.nlm.nih.gov/pubmed/12875977
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