The CD40-CD40L Pathway Contributes to the Proinflammatory Function of Intestinal Epithelial Cells in Inflammatory Bowel Disease

In inflammatory bowel diseases (IBD), intestinal epithelial cells (IECs) are involved in the outbalanced immune responses toward luminal antigens. However, the signals responsible for this proinflammatory capacity of IECs in IBD remain unclear. The CD40/CD40L interaction activates various pathways i...

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Autors principals: Borcherding, Frauke, Nitschke, Martin, Hundorfean, Gheorghe, Rupp, Jan, von Smolinski, Dorthe, Bieber, Katja, van Kooten, Cees, Lehnert, Hendrik, Fellermann, Klaus, Büning, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843472/
https://ncbi.nlm.nih.gov/pubmed/20133813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090461
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