CD40 Ligation on Human Cord Blood CD34(+)Hematopoietic Progenitors Induces Their Proliferation and Differentiation into Functional Dendritic Cells

Human CD34(+) multilineage progenitor cells (CD34HPC) from cord blood and bone marrow express CD40, a member of the tumor necrosis factor–receptor family present on various hematopoietic and nonhematopoietic cells. As hyper-IgM patients with mutated CD40 ligand (CD40L) exhibit neutropenia, no B cell...

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Autores principales: Flores-Romo, Leopoldo, Björck, Pia, Duvert, Valérie, van Kooten, Cees, Saeland, Sem, Banchereau, Jacques
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1997
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196112/
https://ncbi.nlm.nih.gov/pubmed/9016882
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