Cooperation of TLR2 with MyD88, PI3K, and Rac1 in Lipoteichoic Acid–Induced cPLA(2)/COX-2–Dependent Airway Inflammatory Responses

Lipoteichoic acid (LTA) plays a role in the pathogenesis of severe inflammatory responses induced by Gram-positive bacterial infection. Cytosolic phospholipase A(2) (cPLA(2)), cyclooxygenase-2 (COX-2), prostaglandin E(2) (PGE(2)), and interleukin (IL)-6 have been demonstrated to engage in airway inf...

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Detalhes bibliográficos
Main Authors: Lee, I-Ta, Lee, Chiang-Wen, Tung, Wei-Hsuan, Wang, Shyi-Wu, Lin, Chih-Chung, Shu, Jwu-Ching, Yang, Chuen-Mao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843459/
https://ncbi.nlm.nih.gov/pubmed/20167866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090714
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