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Inflammation in gastric cancer: Interplay of the COX‐2/prostaglandin E(2) and Toll‐like receptor/MyD88 pathways

Cyclooxygenase‐2 (COX‐2) and its downstream product prostaglandin E(2) (PGE(2)) play a key role in generation of the inflammatory microenvironment in tumor tissues. Gastric cancer is closely associated with Helicobacter pylori infection, which stimulates innate immune responses through Toll‐like rec...

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Detalles Bibliográficos
Publicado en:Cancer Sci
Main Authors: Echizen, Kanae, Hirose, Osamu, Maeda, Yusuke, Oshima, Masanobu
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832872/
https://ncbi.nlm.nih.gov/pubmed/27079437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12901
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