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Brain Endothelial Cells Synthesize Neurotoxic Thrombin in Alzheimer’s Disease
Alzheimer’s disease (AD) is characterized by neuronal death; thus, identifying neurotoxic proteins and their source is central to understanding and treating AD. The multifunctional protease thrombin is neurotoxic and found in AD senile plaques. The objective of this study was to determine whether br...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Investigative Pathology
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843451/ https://ncbi.nlm.nih.gov/pubmed/20150433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090406 |
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